k atp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1603	Glipizide	CP 28720,K 4024	Potassium Channel , PPAR , ABC
	Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.		Potassium Channel , PPAR , ABC
T15385	Glibornuride		Potassium Channel
	Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.		Potassium Channel
T6541	Ibutilide Fumarate	Corvert Fumarate,U70226E	Calcium Channel , Sodium Channel
	Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outwar...		Calcium Channel , Sodium Channel
T29457L	5-Hydroxydecanoate sodium		Potassium Channel
	5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with IC50 of about 30 μM. 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase with antioxidant p...		Potassium Channel
TQ0150	Levcromakalim	(-)-Cromakalim,BRL 38227	Potassium Channel
	Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.		Potassium Channel
T90604	PCO 400
	PCO 400 is an analog of comakalim that acts as a selective and potent ATP-sensitive K+ channel opener.
T3S0870	Paederosidic acid methyl ester		ATPase , Potassium Channel , NO Synthase
	Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.		ATPase , Potassium Channel , NO Synthase
T1530	Mitiglinide calcium hydrate	KAD-1229 calcium hydrate,Mitiglinide calcium,S-21403 calcium hydrate	Potassium Channel
	Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic ...		Potassium Channel
T4139	D-Luciferin potassium	D-Luciferin K Salt,D-Luciferin Potassium Salt	Others
	D-Luciferin potassium (D-Luciferin K Salt) is a popular bioluminescent substrate of luciferase in the presence of ATP.		Others
T17030	Tegoprazan		ATPase , Proton pump
	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5...		ATPase , Proton pump
T6587	Mitiglinide Calcium	KAD-1229,S21403	ATPase , Potassium Channel
	Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.		ATPase , Potassium Channel
T26086L	1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one		Others
	1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one is an isomer of Rilmakalim, a potassium channel opener (PCO), which can activate ATP-sensitive K+ channels in the heart or other tissues		Others
Fr14207	(-)-Isopulegol		Others
	Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxid...		Others
T16420	P-1075		Potassium Channel
	P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of sulfonylurea receptor 2-associated ATP-sensitive potassium c...		Potassium Channel
T28136	NC-1300-B	NC1300B,NC 1300 B	ATPase
	NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.		ATPase
T14366	AZ10606120 dihydrochloride		P2X Receptor
	AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and ...		P2X Receptor
T2404	Vonoprazan fumarate	TAK-438	ATPase
	Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.		ATPase
T27624	Iptakalim Hydrochloride		Potassium Channel , AChR
	Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2...		Potassium Channel , AChR
T16865	SCH28080		ATPase , Proton pump
	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, an...		ATPase , Proton pump
T2O2668	Oleic acid	Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid	Apoptosis , ATPase , Others , Endogenous Metabolite
	Oleic acid (Glycon Wo) is a natural product, a common saturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ ATPase activator.		Apoptosis , ATPase , Others , Endogenous Metabolite